BCL7A antibody (C-Term)
Quick Overview for BCL7A antibody (C-Term) (ABIN2854648)
Target
See all BCL7A AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- C-Term
-
Characteristics
-
Rabbit Polyclonal antibody to BCL7A (B-cell CLL/lymphoma 7A)
BCL7A antibody [C2C3], C-term -
Purification
- Purified by antigen-affinity chromatography.
-
Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human BCL7A. The exact sequence is proprietary.
-
Isotype
- IgG
-
-
-
-
Application Notes
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
-
Comment
-
Positive Control: HeLaS3 , Neuro2A , GL261
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
-
Preservative
- Thimerosal (Merthiolate)
-
Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))
-
Alternative Name
- BCL7A
-
Background
-
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
-
Molecular Weight
- 23 kDa
-
Gene ID
- 605
Target
-