BCL7A antibody (AA 40-120)

Catalog No. ABIN7224034

This Rabbit Polyclonal antibody specifically detects BCL7A in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for BCL7A antibody (AA 40-120) (ABIN7224034)

Target: BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL7A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BCL7A Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-Bcl-7a Polyclonal Antibody

Specificity: Bcl-7a Polyclonal Antibody detects endogenous levels of Bcl-7a protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Bcl-7a at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BCL7A

Target: BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))

Alternative Name: Bcl-7a

Background: BCL7A, B-cell CLL/lymphoma 7 protein family member ABCL7A (BCL tumor suppressor 7A) is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for BCL7A.

Molecular Weight: 22kD

Gene ID: 605

UniProt: Q4VC05