RAD23A antibody (N-Term)

Catalog No. ABIN2854745

The Rabbit Polyclonal anti-RAD23A antibody has been validated for IF, IHC (fro) and ICC. It is suitable to detect RAD23A in samples from Human and Mouse.

Quick Overview for RAD23A antibody (N-Term) (ABIN2854745)

Target: RAD23A (RAD23 Homolog A (RAD23A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD23A antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-RAD23A Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human

Cross-Reactivity (Details): Human (100 %)

Characteristics: Rabbit polyclonal antibody to RAD23A (RAD23 homolog A (S. cerevisiae))
RAD23A antibody [N1N2], N-term

Purification: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human RAD23A. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF Assay-dependent dilution IHC (Frozen sections) Assay-dependent dilution Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IFAssay-dependent dilution IHC (Frozen sections)Assay-dependent dilution

Comment:

Positive Control: Target recombinant protein

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 6.1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RAD23A

Target: RAD23A (RAD23 Homolog A (RAD23A))

Alternative Name: RAD23A

Background: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Cellular Localization: Nucleus

Molecular Weight: 40 kDa

Gene ID: 5886

Pathways: DNA Damage Repair