Synaptophysin antibody (C-Term)

Catalog No. ABIN2854881

This anti-Synaptophysin antibody is a Rabbit Polyclonal antibody detecting Synaptophysin in WB, IF, IHC (p), ICC, IHC (fro) and IHC (wm). Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for Synaptophysin antibody (C-Term) (ABIN2854881)

Target: Synaptophysin (SYP)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptophysin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Whole Mount) (IHC (wm))

Product Details anti-Synaptophysin Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to Synaptophysin (synaptophysin)
Synaptophysin antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Synaptophysin. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:50000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.65 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-Synaptophysin antibody (ABIN2854881)

Pflügler, Svinka, Scharf, Crncec, Filipits, Charoentong, Tschurtschenthaler, Kenner, Awad, Stift, Schernthanner, Bischl, Herndler-Brandstetter, Glitzner, Moll, Casanova, Timelthaler, Sibilia, Gnant et al.: "IDO1+ Paneth cells promote immune escape of colorectal cancer. ..." in: Communications biology, Vol. 3, Issue 1, pp. 252, (2020) (PubMed).

Pfanzagl, Mechtcheriakova, Meshcheryakova, Aberle, Pfragner, Jensen-Jarolim: "Activation of the ileal neuroendocrine tumor cell line P-STS by acetylcholine is amplified by histamine: role of H3R and H4R." in: Scientific reports, Vol. 7, Issue 1, pp. 1313, (2018) (PubMed).

Target Details for Synaptophysin

Target: Synaptophysin (SYP)

Alternative Name: synaptophysin

Background: Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.[supplied by OMIM]

Cellular Localization: Cytoplasmic vesicle , secretory vesicle , synaptic vesicle membrane, Multi-pass membrane protein , Cell junction , synapse , synaptosome

Molecular Weight: 34 kDa

Gene ID: 6855

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity