Factor XIII antibody

Catalog No. ABIN285491

Product Details anti-Factor XIII Antibody

Target: Factor XIII (F13) (Coagulation Factor XIII (F13))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This Factor XIII antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: This antibody is directed against the alpha-chain of glycophorin. It reacts with normoblasts and erythrocytes in indirect agglutination tests. No reaction occurs with En(a-) erythrocytes and other normal peripheral blood cells.

Purification: Purified

Purity: > 95 % pure

Immunogen: Factor XIII antibody was raised in sheep using purified human factor XIII as the immunogen.

Application Details

Application Notes: ELISA: 10 µg/mL, WB: 10 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Purified IgG supplied in Hepes buffered saline, pH 7.4, with 50 % Glycerol

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for Factor XIII

Target: Factor XIII (F13) (Coagulation Factor XIII (F13))

Alternative Name: Factor XIII (F13 Products)

Background: Factor XIII is a transglutaminase that circulates in the plasma as a heterotetramer of two catalytic A subunits and two carrier B subunits. When thrombin has converted fibrinogen to fibrin, the latter forms a proteinaceous network in which every E-unit is crosslinked to only one D-unit. Factor XIII is activated by thrombin into factor XIIIa, its activation into Factor XIIIa requires calcium as a cofactor.

Molecular Weight: 150 kDa (predicted detection band MW)