F13
Reactivity: Human, Mouse
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 750
Application Notes
Optimal conditions should be determined byt he investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
Lot specific
Buffer
Supplied in liquid form in 10 mM HEPES, pH 7.4, 150 mM NaCl, 50 % (v/v) glycerol
Handling Advice
Avoid repeated freeze/thaw cycles. Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use. Dilute only prior to immediate use.
Factor XIII is a transglutaminase that circulates in the plasma as a heterotetramer of two catalytic A subunits and two carrier B subunits. When thrombin has converted fibrinogen to fibrin, the latter forms a proteinaceous network in which every E-unit is crosslinked to only one D-unit. Factor XIII is activated by thrombin into factor XIIIa, its activation into Factor XIIIa requires calcium as a cofactor. Synonyms: Polyclonal Factor XIII Subunit A antibody, Anti-Factor XIII Subunit A antibody, Complement Factor XIII Subunit A antibody, Fibrin Stabilizing Factor Subunit A antibody.