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HGS antibody (C-Term)

HGS Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855140
  • Target See all HGS Antibodies
    HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))
    Binding Specificity
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 44
    • 31
    • 22
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 38
    • 5
    • 1
    Rabbit
    Clonality
    • 41
    • 3
    Polyclonal
    Conjugate
    • 32
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HGS antibody is un-conjugated
    Application
    • 36
    • 21
    • 20
    • 15
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit Polyclonal antibody to HGS (hepatocyte growth factor-regulated tyrosine kinase substrate)
    HGS antibody [C2C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human HGS. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product HGS Primary Antibody
  • Application Notes
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Validation: Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))
    Alternative Name
    hepatocyte growth factor-regulated tyrosine kinase substrate (HGS Products)
    Synonyms
    HRS antibody, Hrs antibody, fi34f05 antibody, zgc:63492 antibody, wu:fi34f05 antibody, Hgr antibody, ZFYVE8 antibody, CG2903 antibody, Dmel\\CG2903 antibody, HRS-2 antibody, Vps27 antibody, hrs antibody, l(2)23AB5 antibody, l(2)23Ad antibody, l(2)23Ad(Hrs) antibody, vps27 antibody, hgs antibody, hepatocyte growth factor-regulated tyrosine kinase substrate antibody, HGF-regulated tyrosine kinase substrate antibody, Hepatocyte growth factor regulated tyrosine kinase substrate antibody, hepatocyte growth factor-regulated tyrosine kinase substrate L homeolog antibody, HGS antibody, Hgs antibody, hgs antibody, Hrs antibody, hgs.L antibody
    Background
    The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.

    Cellular Localization: Cytoplasm , Early endosome membrane, Peripheral membrane protein, Cytoplasmic side , Endosome , multivesicular body membrane, Peripheral membrane protein
    Molecular Weight
    86 kDa
    Gene ID
    9146
    UniProt
    O14964
    Pathways
    EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Synaptic Vesicle Exocytosis, EGFR Downregulation
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