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AP2B1 antibody (Internal Region)

AP2B1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855154
  • Target See all AP2B1 Antibodies
    AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))
    Binding Specificity
    • 15
    • 7
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 60
    • 20
    • 16
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Human, Mouse
    Host
    • 58
    • 2
    Rabbit
    Clonality
    • 58
    • 2
    Polyclonal
    Conjugate
    • 29
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This AP2B1 antibody is un-conjugated
    Application
    • 36
    • 24
    • 13
    • 13
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Cross-Reactivity
    Cow (Bovine)
    Cross-Reactivity (Details)
    Bovine (100 %)
    Characteristics
    Rabbit polyclonal antibody to beta-Adaptin (adaptor-related protein complex 1, beta 1 subunit)
    beta-Adaptin antibody [N3C1], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human beta-Adaptin. The exact sequence is proprietary.
    Isotype
    IgG
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  • Application Notes
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    Comment

    Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , NIH-3T3

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.55 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))
    Alternative Name
    beta-Adaptin (AP2B1 Products)
    Synonyms
    5-HT(2B) antibody, 5-HT2B antibody, ADTB2 antibody, AP105B antibody, AP2-BETA antibody, CLAPB1 antibody, 1300012O03Rik antibody, AI788979 antibody, fa16e07 antibody, wu:fa16c06 antibody, wu:fa16e07 antibody, wu:fc18c08 antibody, zgc:55659 antibody, 5-hydroxytryptamine receptor 2B antibody, adaptor related protein complex 2 beta 1 subunit antibody, adaptor-related protein complex 2, beta 1 subunit antibody, adaptor related protein complex 2 beta 1 subunit L homeolog antibody, HTR2B antibody, AP2B1 antibody, Ap2b1 antibody, ap2b1 antibody, ap2b1.L antibody
    Background
    Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Two transcript variants encoding different isoforms have been found for this gene, and variants utilizing alternative polyadenylation signals exist.

    Cellular Localization: Golgi apparatus , Cytoplasmic vesicle , clathrin-coated vesicle membrane
    Molecular Weight
    105 kDa
    Gene ID
    162
    Pathways
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
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