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MYB antibody (Internal Region)

MYB Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855353
  • Target See all MYB Antibodies
    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
    Binding Specificity
    • 15
    • 11
    • 11
    • 10
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 113
    • 52
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 95
    • 20
    • 3
    • 2
    Rabbit
    Clonality
    • 101
    • 19
    Polyclonal
    Conjugate
    • 77
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYB antibody is un-conjugated
    Application
    • 92
    • 56
    • 44
    • 23
    • 22
    • 13
    • 13
    • 11
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Mouse (Murine), Cow (Bovine)
    Cross-Reactivity (Details)
    Mouse (83 %), Bovine (91 %)
    Characteristics
    Rabbit Polyclonal antibody to c-Myb (v-myb myeloblastosis viral oncogene homolog (avian))
    c-Myb antibody [N2C1], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human c-Myb. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product MYB Primary Antibody
  • Application Notes
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    Comment

    Positive Control: A549 , HeLa , HepG2 , HCT116

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
    Alternative Name
    C-Myb (MYB Products)
    Synonyms
    Cmyb antibody, c-myb antibody, c-myb_CDS antibody, efg antibody, AI550390 antibody, M16449 antibody, cmyb antibody, xmyb antibody, MYB proto-oncogene, transcription factor antibody, myeloblastosis oncogene antibody, MYB proto-oncogene, transcription factor S homeolog antibody, v-myb avian myeloblastosis viral oncogene homolog antibody, MYB antibody, Myb antibody, myb.S antibody, myb antibody
    Background
    This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.

    Cellular Localization: Nucleus
    Molecular Weight
    72 kDa
    Gene ID
    4602
    Pathways
    Chromatin Binding, Positive Regulation of Immune Effector Process
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