ING1 antibody (C-Term)

Catalog No. ABIN2855405

The Rabbit Polyclonal anti-ING1 antibody has been validated for WB. It is suitable to detect ING1 in samples from Human.

Quick Overview for ING1 antibody (C-Term) (ABIN2855405)

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ING1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ING1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to ING1 (inhibitor of growth family, member 1)
ING1 antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ING1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431 , HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ING1

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Alternative Name: inhibitor of growth family member 1

Background: This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Cellular Localization: Nucleus

Molecular Weight: 47 kDa

Gene ID: 3621

UniProt: Q9UK53

Pathways: Protein targeting to Nucleus, Autophagy