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IMPDH1 antibody (Inosine 5'-Phosphate Dehydrogenase 1) (Center) Primary Antibody

IMPDH1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855489
$509.08
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100 μL
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  • Target See all IMPDH1 Antibodies
    IMPDH1
    Binding Specificity
    • 14
    • 10
    • 10
    • 9
    • 9
    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 62
    • 22
    • 22
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 58
    • 4
    Rabbit
    Clonality
    • 61
    • 1
    Polyclonal
    Conjugate
    • 22
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IMPDH1 antibody is un-conjugated
    Application
    • 48
    • 34
    • 34
    • 15
    • 13
    • 12
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Mouse (Murine), Rat (Rattus), Xenopus laevis, Cow (Bovine), Xenopus tropicalis
    Cross-Reactivity (Details)
    Mouse (95 %), Rat (82 %), Xenopus laevis (88 %), Bovine (97 %), Xenopus tropicalis (89 %)
    Characteristics
    Rabbit polyclonal antibody to IMP dehydrogenase 1 (IMP (inosine monophosphate) dehydrogenase 1)
    IMPDH1 antibody [N1C1]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human IMPDH1. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    Comment

    Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    IMPDH1
    Alternative Name
    IMP Dehydrogenase 1 (IMPDH1 Products)
    Synonyms
    IMPD, IMPD1, LCA11, RP10, sWSS2608, B930086D20Rik, IMPD 1, IMPDH 1, D3, IMPD 1b, IMPDH 1b, IMPDH1, id:ibd5035, si:dkey-31f5.7, wu:fa09h11, wu:fa99c03, zgc:113446, imp, imp1, imp2, inosine monophosphate dehydrogenase 1, inosine-5'-monophosphate dehydrogenase 1, IMP (inosine 5'-monophosphate) dehydrogenase 1b, IMP (inosine 5'-monophosphate) dehydrogenase 1, IMPDH1, Impdh1, LOC100442769, impdh1, impdh1b, impdh1.L
    Background
    The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

    Molecular Weight
    55 kDa
    Gene ID
    3614
    Pathways
    Ribonucleoside Biosynthetic Process
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