MCC antibody (Center)

Catalog No. ABIN2855513

The Rabbit Polyclonal anti-MCC antibody is suitable to detect MCC in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for MCC antibody (Center) (ABIN2855513)

Target: MCC (Mutated in Colorectal Cancers (MCC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MCC Antibody

Binding Specificity: Center

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Xenopus tropicalis

Cross-Reactivity (Details): Mouse (97 %), Rat (97 %), Bovine (96 %), Xenopus tropicalis (92 %)

Characteristics: Rabbit Polyclonal antibody to MCC (mutated in colorectal cancers)
MCC antibody [N1N3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MCC. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: IMR32 , U87-MG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MCC

Target: MCC (Mutated in Colorectal Cancers (MCC))

Alternative Name: MCC

Background: This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 93 kDa

Gene ID: 4163