LAMP2 antibody

Catalog No. ABIN2855580

This anti-LAMP2 antibody is a Rabbit Polyclonal antibody detecting LAMP2 in WB, ICC, IF and IHC (p). Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for LAMP2 antibody (ABIN2855580)

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAMP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Product Details anti-LAMP2 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to LAMP2 (lysosomal-associated membrane protein 2)
LAMP2 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human LAMP2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validatio: KO/KD, Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.63 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-LAMP2 antibody (ABIN2855580)

Kuo, Lin, Hsu, Chen, Yang, Wu: "Noninvasive assessment of characteristics of novel anti-HER2 antibodies by molecular imaging in a human gastric cancer xenograft-bearing mouse model." in: Scientific reports, Vol. 8, Issue 1, pp. 13735, (2019) (PubMed).

Izumi, Li, Shibaki, Mori, Yasunami, Sato, Matsunaga, Mae, Kodama, Kamijo, Kaneko, Nakagawara: "Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region." in: Scientific reports, Vol. 9, Issue 1, pp. 2236, (2019) (PubMed).

Target Details for LAMP2

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Alternative Name: lysosomal associated membrane protein 2

Background: The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins.

Cellular Localization: Cell membrane, Single-pass type I membrane protein , Endosome membrane, Single-pass type I membrane protein , Lysosome membrane, Single-pass type I membrane protein

Molecular Weight: 45 kDa

Gene ID: 3920

UniProt: P13473

Pathways: Autophagy