ARHGAP4 antibody (N-Term)

Catalog No. ABIN2855593

Product Details anti-ARHGAP4 Antibody

Target: ARHGAP4 (rho GTPase Activating Protein 4 (ARHGAP4))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to ARHGAP4 (Rho GTPase activating protein 4)
ARHGAP4 antibody [N1N2], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human ARHGAP4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ARHGAP4

Target: ARHGAP4 (rho GTPase Activating Protein 4 (ARHGAP4))

Alternative Name: Rho GTPase activating protein 4 (ARHGAP4 Products)

Synonyms: zgc:63672 antibody, ARHGAP4 antibody, C1 antibody, RGC1 antibody, RhoGAP4 antibody, SrGAP4 antibody, p115 antibody, A130009C12Rik antibody, A530015A20Rik antibody, Rgc1 antibody, c1 antibody, mKIAA0131 antibody, Rho GTPase activating protein 4a antibody, Rho GTPase activating protein 4 antibody, arhgap4a antibody, ARHGAP4 antibody, arhgap4 antibody, Arhgap4 antibody

Background: This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins belonging to the RAS superfamily. The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules. The rat protein stimulates the activity of some Rho GTPases in vitro. Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus. Multiple transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Cytoplasm

Molecular Weight: 105 kDa

Gene ID: 393

UniProt: P98171

Pathways: Neurotrophin Signaling Pathway, Regulation of Cell Size