PSMA5 antibody (Center)

Catalog No. ABIN2855714

Product Details anti-PSMA5 Antibody

Target: PSMA5 (Proteasome Subunit alpha 5 (PSMA5))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Pig (Porcine), Rhesus Monkey, Cow (Bovine)

Cross-Reactivity (Details): Pig (100 %), Rhesus Monkey (100 %), Bovine (100 %)

Characteristics: Rabbit Polyclonal antibody to PSMA5 (proteasome (prosome, macropain) subunit, alpha type, 5)
PSMA5 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PSMA5. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:10000*

Comment:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , mouse brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PSMA5

Target: PSMA5 (Proteasome Subunit alpha 5 (PSMA5))

Alternative Name: PSMA5 (PSMA5 Products)

Synonyms: 154644_at antibody, Alpha-5 antibody, CG10938 antibody, Dmel\\CG10938 antibody, PRCZ antibody, PSA5_DROME antibody, PSMA5 antibody, ProsMA5 antibody, alpha5 antibody, alpha5_dm antibody, prosMA5 antibody, DDBDRAFT_0216562 antibody, DDBDRAFT_0232930 antibody, DDB_0216562 antibody, DDB_0232930 antibody, ZETA antibody, PSC5 antibody, zgc:86851 antibody, Proteasome alpha5 subunit antibody, proteasome subunit alpha type 5, putative antibody, proteasome subunit alpha type 5 antibody, 20S proteasome subunit alpha-5 antibody, proteasome (prosome, macropain) subunit, alpha type 5 antibody, proteasome subunit alpha 5 antibody, proteasome subunit alpha 5 S homeolog antibody, proteasome (prosome, macropain) subunit, alpha type, 5 antibody, Prosalpha5 antibody, PF07_0112 antibody, CNH01360 antibody, cgd5_1820 antibody, PSA5 antibody, psmA5 antibody, NAEGRDRAFT_55551 antibody, LOC100282220 antibody, LOC100283546 antibody, Psma5 antibody, PSMA5 antibody, psma5.S antibody, psma5 antibody

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.

Cellular Localization: Cytoplasm , Nucleus

Molecular Weight: 26 kDa

Gene ID: 5686

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA