AK4 antibody

Catalog No. ABIN2855826

This anti-AK4 antibody is a Rabbit Polyclonal antibody detecting AK4 in WB, IF, IHC, IHC (p) and ICC. Suitable for Human.

Quick Overview for AK4 antibody (ABIN2855826)

Target: AK4 (Adenylate Kinase 4 (AK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AK4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-AK4 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to Adenylate kinase 3 (adenylate kinase 3-like 1)
Adenylate kinase 3 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Adenylate kinase 4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for AK4

Target: AK4 (Adenylate Kinase 4 (AK4))

Alternative Name: adenylate kinase 4

Background: This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.

Cellular Localization: Mitochondrion matrix

Molecular Weight: 25 kDa

Gene ID: 205

UniProt: P27144

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process