Dystrobrevin beta antibody

Catalog No. ABIN2855857

This Rabbit Polyclonal antibody specifically detects Dystrobrevin beta in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Dystrobrevin beta antibody (ABIN2855857)

Target: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dystrobrevin beta antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Dystrobrevin beta Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to Dystrobrevin beta (dystrobrevin, beta)
Dystrobrevin beta antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Dystrobrevin beta. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse muscle

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.81 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Dystrobrevin beta

Target: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Alternative Name: dystrobrevin beta

Background: This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.

Cellular Localization: Cytoplasm

Molecular Weight: 71 kDa

Gene ID: 1838

UniProt: O60941