TNKS2 antibody (N-Term)

Catalog No. ABIN2855877

The Rabbit Polyclonal anti-TNKS2 antibody (ABIN2855877) specifically detects TNKS2 in WB, IF and ICC. The antibody is reactive with Human samples.

Quick Overview for TNKS2 antibody (N-Term) (ABIN2855877)

Target: TNKS2 (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNKS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-TNKS2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to Tankyrase 2 (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2)
Tankyrase 2 antibody [N1], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Tankyrase 2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TNKS2

Target: TNKS2 (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2))

Alternative Name: tankyrase 2

Background: May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.

Cellular Localization: Cytoplasm , Golgi apparatus membrane, Peripheral membrane protein , Nucleus , Telomere (Potential)

Molecular Weight: 127 kDa

Gene ID: 80351

UniProt: Q9H2K2