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TICAM1 antibody (C-Term)

TICAM1 Reactivity: Human WB, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855929
  • Target See all TICAM1 Antibodies
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    Binding Specificity
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 24
    • 9
    • 3
    • 2
    Human
    Host
    • 22
    • 3
    • 3
    Rabbit
    Clonality
    • 25
    • 3
    Polyclonal
    Conjugate
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TICAM1 antibody is un-conjugated
    Application
    • 20
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit polyclonal antibody to TRIF (toll-like receptor adaptor molecule 1)
    TRIF antibody [C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TRIF. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product TICAM1 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: HeLa

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.01 mg/mL
    Buffer
    1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Mlcochova, Winstone, Zuliani-Alvarez, Gupta: "TLR4-Mediated Pathway Triggers Interferon-Independent G0 Arrest and Antiviral SAMHD1 Activity in Macrophages." in: Cell reports, Vol. 30, Issue 12, pp. 3972-3980.e5, (2020) (PubMed).

  • Target
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    Alternative Name
    toll like receptor adaptor molecule 1 (TICAM1 Products)
    Synonyms
    IIAE6 antibody, MyD88-3 antibody, PRVTIRB antibody, TICAM-1 antibody, TRIF antibody, AW046014 antibody, AW547018 antibody, trif antibody, toll like receptor adaptor molecule 1 antibody, toll-like receptor adaptor molecule 1 antibody, TICAM1 antibody, Ticam1 antibody, ticam1 antibody
    Background
    TRIF, or TICAM1, is a Toll/IL1R (MIM 147810) (TIR) domain-containing adaptor molecule, like MYD88 (MIM 602170) and TIRAP (MIM 606252), that induces interferon-beta (IFNB, MIM 147640), specifically interacts with TLR3 (MIM 603029), and activates nuclear factor kappa-B (NFKB, see MIM 164011).[supplied by OMIM]

    Molecular Weight
    76 kDa
    Gene ID
    148022
    UniProt
    Q8IUC6
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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