FBXL12 antibody (C-Term)

Catalog No. ABIN2855977

This Rabbit Polyclonal antibody specifically detects FBXL12 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for FBXL12 antibody (C-Term) (ABIN2855977)

Target: FBXL12 (F-Box and Leucine-Rich Repeat Protein 12 (FBXL12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXL12 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FBXL12 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to FBXL12 (F-box and leucine-rich repeat protein 12)
FBXL12 antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FBXL12. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: NIH-3T3 , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FBXL12

Target: FBXL12 (F-Box and Leucine-Rich Repeat Protein 12 (FBXL12))

Alternative Name: F-box and leucine rich repeat protein 12

Background: Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM]

Molecular Weight: 37 kDa

Gene ID: 54850

UniProt: Q9NXK8

Pathways: SARS-CoV-2 Protein Interactome