MEF2C antibody

Catalog No. ABIN2856105

This anti-MEF2C antibody is a Rabbit Polyclonal antibody detecting MEF2C in WB, IHC, IF, IHC (p), ICC, IHC (fro) and IP. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for MEF2C antibody (ABIN2856105)

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Product Details anti-MEF2C Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to MEF2C (myocyte enhancer factor 2C)
MEF2C antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MEF2C. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IP: 1:100-1:500. IHC: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validation: Comparison

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.32 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-MEF2C antibody (ABIN2856105)

Zhang, Zhang, Nam: "Stoichiometric optimization of Gata4, Hand2, Mef2c, and Tbx5 expression for contractile cardiomyocyte reprogramming." in: Scientific reports, Vol. 9, Issue 1, pp. 14970, (2019) (PubMed).

Target Details for MEF2C

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Alternative Name: myocyte enhancer factor 2C

Background: This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.

Cellular Localization: Nucleus

Molecular Weight: 51 kDa

Gene ID: 4208

UniProt: Q06413

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling