GBP1 antibody (Internal Region)

Catalog No. ABIN2856187

This Rabbit Polyclonal antibody specifically detects GBP1 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for GBP1 antibody (Internal Region) (ABIN2856187)

Target: GBP1 (Guanylate Binding Protein 1, Interferon-Inducible (GBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GBP1 Antibody

Binding Specificity: Internal Region

Characteristics: Rabbit Polyclonal antibody to GBP1 (guanylate binding protein 1, interferon-inducible, 67 kDa)
GBP1 antibody [N2C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GBP1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: A431 , HeLaS3 , HepG2 , Molt-4 , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GBP1

Target: GBP1 (Guanylate Binding Protein 1, Interferon-Inducible (GBP1))

Alternative Name: GBP1

Background: Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3.

Cellular Localization: Cell membrane, Lipid-anchor, Cytoplasmic side

Molecular Weight: 68 kDa

Gene ID: 2633

Pathways: Cellular Response to Molecule of Bacterial Origin