Monoamine Oxidase B antibody

Catalog No. ABIN2856231

Cited in 1 publication. The Rabbit Polyclonal anti-Monoamine Oxidase B antibody (ABIN2856231) specifically detects Monoamine Oxidase B in WB, ELISA, IHC, IHC (p), IF and ICC. The antibody is reactive with Human samples.

Quick Overview for Monoamine Oxidase B antibody (ABIN2856231)

Target: Monoamine Oxidase B (MAOB)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Monoamine Oxidase B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-Monoamine Oxidase B Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to Monoamine Oxidase B (monoamine oxidase B)
Monoamine Oxidase B antibody [N2C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Monoamine Oxidase B. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse liver

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.88 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-Monoamine Oxidase B antibody (ABIN2856231)

Yang, Chien, Lai, Su, Jan, Hsiao, Chen: "Monoamine Oxidase B Expression Correlates with a Poor Prognosis in Colorectal Cancer Patients and Is Significantly Associated with Epithelial-to-Mesenchymal Transition-Related Gene Signatures." in: International journal of molecular sciences, Vol. 21, Issue 8, (2020) (PubMed).

Target Details for Monoamine Oxidase B

Target: Monoamine Oxidase B (MAOB)

Alternative Name: monoamine oxidase B

Background: The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine.

Cellular Localization: Mitochondrion outer membrane

Molecular Weight: 59 kDa

Gene ID: 4129

UniProt: P27338