GABBR2 antibody

Catalog No. ABIN2856236

The Rabbit Polyclonal anti-GABBR2 antibody has been validated for WB and IHC (fro). It is suitable to detect GABBR2 in samples from Human.

Quick Overview for GABBR2 antibody (ABIN2856236)

Target: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABBR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GABBR2 Antibody

Cross-Reactivity: Human, Rat

Characteristics: Rabbit Polyclonal antibody to GABA B Receptor 2 (gamma-aminobutyric acid (GABA) B receptor, 2)
GABA B Receptor 2 antibody [N2C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GABA B Receptor 2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG , unboiled Myc-DDK-tagged Gabbr2-transfected 293T

Validation: Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.83 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GABBR2

Target: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Alternative Name: gamma-aminobutyric acid type B receptor subunit 2

Background: B-type receptors for the neurotransmitter GABA (gamma-aminobutyric acid) inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters and the activity of ion channels and adenylyl cyclase. See GABBR1 (MIM 603540) for additional background information on GABA-B receptors.[supplied by OMIM]

Cellular Localization: Cell membrane, Multi-pass membrane protein , Cell junction , synapse , postsynaptic cell membrane, Multi-pass membrane protein

Molecular Weight: 106 kDa

Gene ID: 9568

UniProt: O75899

Pathways: cAMP Metabolic Process