ERLIN2 antibody (C-Term)

Catalog No. ABIN2856296

The Rabbit Polyclonal anti-ERLIN2 antibody has been validated for WB and IHC (p). It is suitable to detect ERLIN2 in samples from Human.

Quick Overview for ERLIN2 antibody (C-Term) (ABIN2856296)

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERLIN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ERLIN2 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to ERLIN2 (ER lipid raft associated 2)
SPFH2 antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SPFH2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLaS3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.41 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ERLIN2

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Alternative Name: ER lipid raft associated 2

Background: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway.

Cellular Localization: Endoplasmic reticulum membrane, Single-pass type II membrane protein

Molecular Weight: 38 kDa

Gene ID: 11160

UniProt: O94905