DISC1 antibody (N-Term)

Catalog No. ABIN2856299

The Rabbit Polyclonal anti-DISC1 antibody has been validated for WB. It is suitable to detect DISC1 in samples from Human.

Quick Overview for DISC1 antibody (N-Term) (ABIN2856299)

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DISC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DISC1 Antibody

Binding Specificity: N-Term

Characteristics: Rabbit polyclonal antibody to DISC1 (disrupted in schizophrenia 1)
DISC1 antibody [N1], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human DISC1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: Molt-4

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DISC1

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Alternative Name: DISC1

Background: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1,11)(q42.1,q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Cellular Localization: Cytoplasm , Centrosome , cytoskeleton

Molecular Weight: 94 kDa

Gene ID: 27185

Pathways: Regulation of Cell Size