SCMH1 antibody (Center)

Catalog No. ABIN2856463

This Rabbit Polyclonal antibody specifically detects SCMH1 in IHC (p), ICC and IF. It exhibits reactivity toward Human.

Quick Overview for SCMH1 antibody (Center) (ABIN2856463)

Target: SCMH1 (Sex Comb On Midleg Homolog 1 (SCMH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCMH1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-SCMH1 Antibody

Binding Specificity: Center

Cross-Reactivity: Cow (Bovine)

Cross-Reactivity (Details): Bovine (100 %)

Characteristics: Rabbit polyclonal antibody to SCMH1 (sex comb on midleg homolog 1 (Drosophila))
SCMH1 antibody [N1N3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SCMH1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*

Comment:

Positive Control: 293T , H1299 , HepG2 , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SCMH1

Target: SCMH1 (Sex Comb On Midleg Homolog 1 (SCMH1))

Alternative Name: SCMH1

Background: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Cellular Localization: Nucleus

Molecular Weight: 73 kDa

Gene ID: 22955