ZC3H8 antibody

Catalog No. ABIN2856471

The Rabbit Polyclonal anti-ZC3H8 antibody (ABIN2856471) specifically detects ZC3H8 in WB, IHC (p), IF and ICC. The antibody is reactive with Human samples.

Quick Overview for ZC3H8 antibody (ABIN2856471)

Target: ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZC3H8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-ZC3H8 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to ZC3H8 (zinc finger CCCH-type containing 8)
ZC3H8 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ZC3H8. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431 , HepG2 , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.84 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ZC3H8

Target: ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))

Alternative Name: zinc finger CCCH-type containing 8

Background: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Cellular Localization: Nucleus

Molecular Weight: 34 kDa

Gene ID: 84524

UniProt: Q8N5P1