IPO13 antibody (C-Term)

Catalog No. ABIN2856550

This Rabbit Polyclonal antibody specifically detects IPO13 in WB, IP and IHC (p). It exhibits reactivity toward Human.

Quick Overview for IPO13 antibody (C-Term) (ABIN2856550)

Target: IPO13 (Importin 13 (IPO13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IPO13 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IPO13 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Rat

Characteristics: Rabbit Polyclonal antibody to Importin 13 (importin 13)
Importin 13 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Importin 13. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: IPO13 transfected 293T , PC-12 , Rat2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.02 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for IPO13

Target: IPO13 (Importin 13 (IPO13))

Alternative Name: importin 13

Background: This gene encodes a member of the importin-beta family of nuclear transport proteins. The encoded protein mediates the import of specific cargo proteins from the cytoplasm to the nucleus and is dependent on the Ras-related nuclear protein-GTPase system. The encoded protein is also involved in nuclear export of the eukaryotic translation initiation factor 1A.

Cellular Localization: Cytoplasm , Nucleus

Molecular Weight: 108 kDa

Gene ID: 9670

UniProt: O94829

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Protein targeting to Nucleus