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IPO13 antibody (AA 501-700) (HRP)

IPO13 Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7156145
  • Target See all IPO13 Antibodies
    IPO13 (Importin 13 (IPO13))
    Binding Specificity
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 501-700
    Reactivity
    • 19
    • 2
    • 2
    • 1
    Human
    Host
    • 19
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IPO13 antibody is conjugated to HRP
    Application
    • 10
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Importin-13 protein (501-700AA)
    Isotype
    IgG
    Top Product
    Discover our top product IPO13 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    IPO13 (Importin 13 (IPO13))
    Alternative Name
    IPO13 (IPO13 Products)
    Synonyms
    3R23 antibody, CG 7212 antibody, CG7212 antibody, Dmel\\CG7212 antibody, Imp13 antibody, imp13 antibody, sd-5 antibody, DDBDRAFT_0205767 antibody, DDBDRAFT_0304414 antibody, DDB_0205767 antibody, DDB_0304414 antibody, DDBDRAFT_0191787 antibody, DDBDRAFT_0304413 antibody, DDB_0191787 antibody, DDB_0304413 antibody, IMP13 antibody, KAP13 antibody, LGL2 antibody, RANBP13 antibody, Kap13 antibody, Ranbp13 antibody, Lgl2 antibody, DKFZp459H088 antibody, cadmus antibody, importin 13 antibody, cdm antibody, IPO13 antibody, AFUA_5G08060 antibody, ANI_1_1340034 antibody, AOR_1_1272114 antibody, ipo13B antibody, ipo13A antibody, ipo13 antibody, Ipo13 antibody
    Background

    Background: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of UBC9, the RBM8A/MAGOH complex, PAX6 and probably other members of the paired homeobox family. Also mediates nuclear export of eIF-1A, and the cytoplasmic release of eIF-1A is triggered by the loading of import substrates onto IPO13.

    Aliases: Imp 13 antibody, Imp13 antibody, Importin-13 antibody, Importin13 antibody, IPO 13 antibody, Ipo13 antibody, IPO13_HUMAN antibody, Kap 13 antibody, Kap13 antibody, Karyopherin 13 antibody, Karyopherin-13 antibody, Karyopherin13 antibody, KIAA0274 antibody, Late gestation lung 2 antibody, Late gestation lung 2 protein antibody, Lgl2 antibody, Ran binding protein 13 antibody, Ran-binding protein 13 antibody, RanBP 13 antibody, RanBP13 antibody

    UniProt
    O94829
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Protein targeting to Nucleus
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