TIMM17A antibody (C-Term)

Catalog No. ABIN2856587

The Rabbit Polyclonal anti-TIMM17A antibody has been validated for WB, IF and ICC. It is suitable to detect TIMM17A in samples from Human. There is 1 publication available.

Quick Overview for TIMM17A antibody (C-Term) (ABIN2856587)

Target: TIMM17A (Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMM17A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-TIMM17A Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit polyclonal antibody to Tim17 (translocase of inner mitochondrial membrane 17 homolog A (yeast))
TIM17 antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TIM17. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-TIMM17A antibody (ABIN2856587)

Sprenger, Wani, Hesseling, König, Patron, MacVicar, Ahola, Wai, Barth, Rugarli, Bergami, Langer: "Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy." in: EMBO molecular medicine, Vol. 11, Issue 1, (2019) (PubMed).

Target Details for TIMM17A

Target: TIMM17A (Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A))

Alternative Name: translocase of inner mitochondrial membrane 17A

Background: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

Cellular Localization: Mitochondrion inner membrane, Multi-pass membrane protein

Molecular Weight: 18 kDa

Gene ID: 10440

UniProt: Q99595