FGG antibody

Catalog No. ABIN2856626

The Rabbit Polyclonal anti-FGG antibody has been validated for WB, IP, ICC, IF and IHC (p). It is suitable to detect FGG in samples from Human.

Quick Overview for FGG antibody (ABIN2856626)

Target: FGG (Fibrinogen gamma Chain (FGG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGG antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FGG Antibody

Cross-Reactivity: Cow, Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to Fibrinogen gamma (fibrinogen gamma chain)
Fibrinogen gamma antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Fibrinogen gamma. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: rat plasma

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.77 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FGG

Target: FGG (Fibrinogen gamma Chain (FGG))

Alternative Name: fibrinogen gamma chain

Background: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Cellular Localization: Secreted

Molecular Weight: 52 kDa

Gene ID: 2266

UniProt: P02679