TEAD4 antibody (Center)

Catalog No. ABIN2856634

This Rabbit Polyclonal antibody specifically detects TEAD4 in WB and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for TEAD4 antibody (Center) (ABIN2856634)

Target: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TEAD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TEAD4 Antibody

Binding Specificity: Center

Cross-Reactivity: Mouse (Murine), Pig (Porcine)

Cross-Reactivity (Details): Mouse (91 %), Pig (94 %)

Characteristics: Rabbit Polyclonal antibody to TEAD4 (TEA domain family member 4)
TEAD4 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TEAD4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: HepG2 necleus

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-TEAD4 antibody (ABIN2856634)

Zhang, Li, Wu, Ge, Song, Wang, Yuan, Jiang, Wang, Cheng: "TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma." in: Cancer cell international, Vol. 18, pp. 178, (2018) (PubMed).

Target Details for TEAD4

Target: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Alternative Name: TEAD4

Background: This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.

Cellular Localization: Nucleus

Molecular Weight: 48 kDa

Gene ID: 7004

Pathways: Regulation of Lipid Metabolism by PPARalpha