slc25a13 antibody

Catalog No. ABIN2856647

The Rabbit Polyclonal anti-slc25a13 antibody is suitable to detect slc25a13 in samples from Human. It has been validated for WB, ICC, IF and IHC (p).

Quick Overview for slc25a13 antibody (ABIN2856647)

Target: slc25a13 (Solute Carrier Family 25, Member 13 (Citrin) (slc25a13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This slc25a13 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Product Details anti-slc25a13 Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to SLC25A13 (solute carrier family 25, member 13 (citrin))
SLC25A13 antibody [N3C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SLC25A13. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse liver , rat liver , 293T , A431 , HeLa , HepG2

Validation: Comparison, KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.61 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for slc25a13

Target: slc25a13 (Solute Carrier Family 25, Member 13 (Citrin) (slc25a13))

Alternative Name: solute carrier family 25 member 13

Background: This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Mitochondrion inner membrane

Molecular Weight: 74 kDa

Gene ID: 10165

UniProt: Q9UJS0

Pathways: Ribonucleoside Biosynthetic Process, Dicarboxylic Acid Transport