PRKAG2 antibody (full length)

Catalog No. ABIN2856652

Product Details anti-PRKAG2 Antibody

Target: PRKAG2 (Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))

Binding Specificity: full length

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKAG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Characteristics: Rabbit Polyclonal antibody to AMPK gamma 2 (protein kinase, AMP-activated, gamma 2 non-catalytic subunit)
AMPK gamma 2 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human AMPK gamma 2 Recombinant protein.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PRKAG2

Target: PRKAG2 (Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))

Alternative Name: AMPK gamma 2 (PRKAG2 Products)

Synonyms: MGC82938 antibody, PRKAG2 antibody, si:ch211-230l11.1 antibody, si:dkey-217f4.2 antibody, AAKG antibody, AAKG2 antibody, CMH6 antibody, H91620p antibody, WPWS antibody, 2410051C13Rik antibody, AI854673 antibody, protein kinase AMP-activated non-catalytic subunit gamma 2 antibody, protein kinase, AMP-activated, gamma 2 non-catalytic subunit L homeolog antibody, 5'-AMP-activated protein kinase subunit gamma-2 antibody, protein kinase, AMP-activated, gamma 2 non-catalytic subunit b antibody, protein kinase, AMP-activated, gamma 2 non-catalytic subunit antibody, Prkag2 antibody, PRKAG2 antibody, prkag2.L antibody, LOC504219 antibody, prkag2b antibody, prkag2 antibody

Background: AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 63 kDa

Gene ID: 51422

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process, Ribonucleoside Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Warburg Effect