MLYCD antibody

Catalog No. ABIN2856728

Product Details anti-MLYCD Antibody

Target: MLYCD (Malonyl CoA Decarboxylase (MLYCD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLYCD antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to MCD (malonyl-CoA decarboxylase)
MCD antibody [N2C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MCD. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: C8D30

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MLYCD

Target: MLYCD (Malonyl CoA Decarboxylase (MLYCD))

Alternative Name: malonyl-CoA decarboxylase (MLYCD Products)

Synonyms: MCD antibody, AI324784 antibody, Mcd antibody, MaLonyl CoA Decarboxylase antibody, malonyl-CoA decarboxylase antibody, mlcd-1 antibody, MLYCD antibody, Mlycd antibody

Background: The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency.

Cellular Localization: Mitochondrion , Cytoplasm , Peroxisome

Molecular Weight: 55 kDa

Gene ID: 23417

UniProt: O95822

Pathways: Regulation of Carbohydrate Metabolic Process