PSAT1 antibody

Catalog No. ABIN2856767

The Rabbit Polyclonal anti-PSAT1 antibody has been validated for WB, IF, ICC and IHC (p). It is suitable to detect PSAT1 in samples from Human. There are 2+ publications available.

Quick Overview for PSAT1 antibody (ABIN2856767)

Target: PSAT1 (phosphoserine Aminotransferase 1 (PSAT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Product Details anti-PSAT1 Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to PSAT1 (phosphoserine aminotransferase 1)
PSAT1 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PSAT1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse brain , A549 , H1299 , HCT116 , 293T

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.33 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-PSAT1 antibody (ABIN2856767)

Tripodi, Motta, Murtas, Rabattoni, Nonnis, Grassi Scalvini, Rinaldi, Rizzi, Bearzi, Badone, Sacchi, Tedeschi, Maffioli, Coccetti, Pollegioni: "Serine metabolism during differentiation of human iPSC-derived astrocytes." in: The FEBS journal, (2023) (PubMed).

Maffioli, Murtas, Rabattoni, Badone, Tripodi, Iannuzzi, Licastro, Nonnis, Rinaldi, Motta, Sacchi, Canu, Tedeschi, Coccetti, Pollegioni: "Insulin and serine metabolism as sex-specific hallmarks of Alzheimer's disease in the human hippocampus." in: Cell reports, Vol. 40, Issue 10, pp. 111271, (2022) (PubMed).

Target Details for PSAT1

Target: PSAT1 (phosphoserine Aminotransferase 1 (PSAT1))

Alternative Name: phosphoserine aminotransferase 1

Background: The protein encoded by this gene is likely a phosphoserine aminotransferase, based on similarity to proteins in mouse, rabbit, and Drosophila. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Molecular Weight: 40 kDa

Gene ID: 29968

UniProt: Q9Y617

Pathways: Warburg Effect