SHC4 antibody (Center)

Catalog No. ABIN2856800

The Rabbit Polyclonal anti-SHC4 antibody is suitable to detect SHC4 in samples from Human. It has been validated for WB.

Quick Overview for SHC4 antibody (Center) (ABIN2856800)

Target: SHC4 (SHC (Src Homology 2 Domain Containing) Family, Member 4 (SHC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SHC4 Antibody

Binding Specificity: Center

Cross-Reactivity: Cow (Bovine)

Cross-Reactivity (Details): Bovine (87 %)

Characteristics: Rabbit polyclonal antibody to SHC4 (SHC (Src homology 2 domain containing) family, member 4)
SHC4 antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SHC4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: A431 , Molt-4

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.54 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SHC4

Target: SHC4 (SHC (Src Homology 2 Domain Containing) Family, Member 4 (SHC4))

Alternative Name: SHC4

Background: Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.

Cellular Localization: Cell junction , synapse , postsynaptic cell membrane

Molecular Weight: 69 kDa

Gene ID: 399694