ATP1A1 antibody

Catalog No. ABIN285875

The Rabbit Polyclonal anti-ATP1A1 antibody is suitable to detect ATP1A1 in samples from Human, Rat and Cow. It has been validated for WB, IP and ICC.

Quick Overview for ATP1A1 antibody (ABIN285875)

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Reactivity: Human, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-ATP1A1 Antibody

Cross-Reactivity (Details): Rat and Bovine. Does not cross react with rabbit.1 mg/ml

Purification: purified

Immunogen: Na+/K+ ATPase alpha 1 antibody was raised in rabbit using GST-tagged ATPase as the immunogen.

Isotype: IgG

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Protein A purified rabbit IgG supplied in 100 mM Tris-Glycine, pH 7.4, with 150 M NaCl and 0.05 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for ATP1A1

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Alternative Name: Na, K, ATPase alpha 1

Background: Na+/K+-ATPase (also known as the Na+/K+ pump or sodium-potassium pump) is an enzyme located in the plasma membrane (specifically an electrogenic transmembrane ATPase). It is found in the plasma membrane of virtually every human cell and is common to all cellular life. It helps maintain cell potential and regulate cellular volume. In order to maintain the appropriate concentrations, the sodium-potassium pump pumps sodium out and potassium in through active transport.

Molecular Weight: 112 kDa (predicted detection band MW)

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process