Chromogranin A antibody

Catalog No. ABIN285904

This Rabbit Polyclonal antibody specifically detects Chromogranin A in IHC (p), ICC and IHC (fro). It exhibits reactivity toward Human and Pig.

Quick Overview for Chromogranin A antibody (ABIN285904)

Target: Chromogranin A (CHGA)

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Chromogranin A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Chromogranin A Antibody

Immunogen: Pancreastatin antibody was raised in rabbit using synthetic pancreastatin as the immunogen.

Isotype: IgG1

Application Details

Application Notes: IHC-F: 1:50, IHC-P: 1:50
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as whole antiserum containing 0.09 % NaN3.Dilute immediately before use with PBS or TBS.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for Chromogranin A

Target: Chromogranin A (CHGA)

Alternative Name: Pancreastatin

Background: Pancreastatin is a 49-residue peptide hormone that inhibits glucose-induced insulin release and exocrine pancreatic secretion. It was originally isolated from porcine pancreas, where it is colocalized with insulin, glucagon and somatostatin, but it is part of the sequence of chromogranin A and is thus found in tissues where the chromogranin gene is expressed, including most endocrine cells.

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling