Botulinum Neurotoxin Type A antibody

Catalog No. ABIN2859514

The Rabbit Polyclonal anti-Botulinum Neurotoxin Type A antibody is suitable to detect Botulinum Neurotoxin Type A in samples from Clostridium botulinum. It has been validated for WB and EIA.

Quick Overview for Botulinum Neurotoxin Type A antibody (ABIN2859514)

Target: Botulinum Neurotoxin Type A (BoNTA)

Reactivity: Clostridium botulinum

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Botulinum Neurotoxin Type A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Botulinum Neurotoxin Type A Antibody

Purification: Protein G Sepharose Chromatography.

Immunogen: Type A Neurotoxin and Complexing Proteins Toxoid.

Application Details

Application Notes: Suitable for use in Dot blot, ELISA (1/10,000) and Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.5 mg/mL (OD280nm, E0.1%=1.4)

Buffer: 1x PBS, pH 7.2 containing 20 % Glycerol and no preservative.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for Botulinum Neurotoxin Type A

Target: Botulinum Neurotoxin Type A (BoNTA)

Alternative Name: Botulinum Neurotoxin Type A

Background: Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.Synonyms: BOTOX, BoNT/A, Bontoxilysin-A, Clostridium botulinum Toxin A

Gene ID: 1491

UniProt: P10845