Thrombopoietin antibody
Quick Overview for Thrombopoietin antibody (ABIN285976)
Target
See all Thrombopoietin (THPO) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Immunogen
- Thrombopoietin antibody was raised in goat using highly pure recombinant human TPO as the immunogen.
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Application Notes
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ELISA: 0.5-2 µg/mL, Inhibition: 0.05-0.08 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2.
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- Thrombopoietin (THPO)
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Alternative Name
- Thrombopoietin
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Background
- TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and Mouse TPO exhibits cross-species reactivity.
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Molecular Weight
- 18.7 kDa (predicted detection band MW)
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Pathways
- JAK-STAT Signaling, Hormone Activity
Target
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