Resistin antibody (Biotin)

Catalog No. ABIN288464

The Goat Polyclonal anti-Resistin antibody has been validated for WB and ELISA. It is suitable to detect Resistin in samples from Mouse.

Quick Overview for Resistin antibody (Biotin) (ABIN288464)

Target: Resistin (RETN)

Reactivity: Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This Resistin antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Product Details anti-Resistin Antibody (Biotin)

Immunogen: Resistin antibody (biotin) was raised in goat using highly pure recombinant murine resistin as the immunogen.

Application Details

Application Notes: ELISA: 0.25-1 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in sterile PBS with 0.1 % BSA to a concentration of at least 50 µg/mL

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for Resistin

Target: Resistin (RETN)

Alternative Name: Resistin

Background: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis.

Molecular Weight: 20.2 kDa (predicted detection band MW)

Pathways: Feeding Behaviour, Smooth Muscle Cell Migration