IL-11 antibody

Catalog No. ABIN289358

The Rabbit Polyclonal anti-IL-11 antibody has been validated for WB, ELISA and Inhibition. It is suitable to detect IL-11 in samples from Human.

Quick Overview for IL-11 antibody (ABIN289358)

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Product Details anti-IL-11 Antibody

Purification: Purified

Immunogen: IL11 antibody was raised in rabbit using highly pure recombinant hIL-11 as the immunogen.

Application Details

Application Notes: ELISA: 0.5-2 µg/mL, Inhibition: 0.02-0.05 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in sterile water at a concentration of >0.2 mg/mL.

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.4.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for IL-11

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Alternative Name: IL11

Background: IL11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury.

Molecular Weight: 19.1 kDa (predicted detection band MW)

Pathways: JAK-STAT Signaling, Negative Regulation of Hormone Secretion