Growth Hormone 1 antibody

Catalog No. ABIN294957

The Mouse Monoclonal anti-Growth Hormone 1 antibody (Clone GhB9) (ABIN294957) specifically detects Growth Hormone 1 in ELISA. The antibody is reactive with Human samples.

Quick Overview for Growth Hormone 1 antibody (ABIN294957)

Target: Growth Hormone 1 (GH1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Growth Hormone 1 antibody is un-conjugated

Application: ELISA

Clone: GhB9

Product Details anti-Growth Hormone 1 Antibody

Specificity: Recognizes human growth hormone (hGH), a 22kD polypeptide synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. It is also referred to as somatotropin. Many different isoforms exist in humans, from monomers to pentamers, disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. Human GH binds to two GH receptors and induces signal transduction through receptor dimerization. Growth hormone plays an important role in growth and cell production. An excess of GH results in acromegaly or gigantism, characterized by excessive growth. It can also be accompanied by muscle weakness, insulin resistance and pressure on nerves. Deficiency of GH may result in lack of strength, energy and bone mass. May be used to detect human growth hormone in ELISA assays.

Purification: Affinity purified

Immunogen: Purified recombinant human growth hormone.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA

Usage: ELISA: This product may be used in an indirect ELISA

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details for Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Alternative Name: GH / Growth Hormone

Background: Name/Gene ID: GH1
Family: Somatotropin

Synonyms: GH1, Growth hormone, GH, GHN, IGHD1B, GH-N, Pituitary growth hormone, Growth hormone 1, HGH-N, Somatotropin

Gene ID: 2688

UniProt: P01241

Pathways: NF-kappaB Signaling, JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process