Factor 12 Heavy Chain (F12) antibody

Catalog No. ABIN2962710

This Mouse Monoclonal antibody specifically detects Factor 12 Heavy Chain in WB, ELISA, ICC and IP. It exhibits reactivity toward Human.

Quick Overview for Factor 12 Heavy Chain (F12) antibody (ABIN2962710)

Target: Factor 12 Heavy Chain (F12)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: B7C9

Product Details

Specificity: Reacts with human Factor XII Heavy Chain (KD of 9.8nM) and partially blocks Factor XII activity. Suitable for coagulation assays.

Purification: Purified (protein G)

Immunogen: Purified human Factor XII.

Isotype: IgG1

Application Details

Application Notes: Working dilution: Optimal dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4.

Handling Advice: Dilute in PBS or medium that is identical to that used in the assay system.

Storage: -20 °C/-80 °C

Storage Comment: Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Factor 12 Heavy Chain (F12)

Alternative Name: Factor XII Heavy Chain

Background: Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. This single chain zymogen circulates in blood andis converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain wich contains only a catalytic domain.

Coagulation factor XII (EC:3.4.21.38) Hageman factor, HAF Coagulation factor XIIa light chain Beta-factor XIIa part 2 HAE3 HAEX Gene name : F12

Gene ID: 2161

UniProt: P00748