ICAM2 antibody

Catalog No. ABIN2967162

The Mouse Monoclonal anti-ICAM2 antibody is suitable to detect ICAM2 in samples from Human. It has been validated for FACS, IP and IHC (fro).

Quick Overview for ICAM2 antibody (ABIN2967162)

Target: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICAM2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: CBR-IC2-2

Product Details anti-ICAM2 Antibody

Purpose: Anti-Hu CD102 Purified

Cross-Reactivity (Details): Human

Characteristics: The mouse monoclonal antibody CBR-IC2/2 recognizes an extracellular epitope of CD102 (ICAM-2), an approximately 55 kDa type I transmembrane glycoprotein expressed mainly on vascular endothelial cells and folicular dendritic cells, in lower amount on lymphocytes, monocytes and platelets.

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: Human CD102 cDNA transfected COS cells

Isotype: IgG2a

Application Details

Application Notes: Flow cytometry: Recommended dilution: 2-4 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for ICAM2

Target: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Alternative Name: CD102

Background: Intercellular adhesion molecule 2,CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration.,ICAM2

Gene ID: 3384

UniProt: P13598