SMAD6 antibody (AA 257-496)

Catalog No. ABIN3015230

This Rabbit Polyclonal antibody specifically detects SMAD6 in WB. It exhibits reactivity toward Human.

Quick Overview for SMAD6 antibody (AA 257-496) (ABIN3015230)

Target: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMAD6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SMAD6 Antibody

Binding Specificity: AA 257-496

Sequence: PTVCCNPYHF SRLCGPESPP PPYSRLSPRD EYKPLDLSDS TLSYTETEAT NSLITAPGEF SDASMSPDAT KPSHWCSVAY WEHRTRVGRL YAVYDQAVSI FYDLPQGSGF CLGQLNLEQR SESVRRTRSK IGFGILLSKE PDGVWAYNRG EHPIFVNSPT LDAPGGRALV VRKVPPGYSI KVFDFERSGL QHAPEPDAAD GPYDPNSVRI SFAKGWGPCY SRQFITSCPC WLEILLNNPR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 257-496 of human Smad6 (NP_005576.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SMAD6

Target: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Alternative Name: SMAD6

Background: The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.,SMAD6,AOVD2,HsT17432,MADH6,MADH7,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,TGF-b-Smad Signaling Pathway,Stem Cells,Cardiovascular,Heart,Cardiogenesis,Hypertrophy,SMADs,SMAD6

Molecular Weight: 26 kDa/35 kDa/53 kDa

Gene ID: 4091

UniProt: O43541

Pathways: Chromatin Binding