SMAD6 antibody (AA 358-386)
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- Target See all SMAD6 Antibodies
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
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Binding Specificity
- AA 358-386
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SMAD6 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Cross-Reactivity (Details)
- Expected species reactivity: Mouse
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 358-386 from the human protein was used as the immunogen for this SMAD6 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SMAD6 Primary Antibody
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anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 1-496) antibody
SMAD6 Reactivity: Human WB, IP, IF Host: Rabbit Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-384) antibodySMAD6 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 2A6 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-384) antibodySMAD6 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 1G2 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 261-495) antibodySMAD6 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 137-182) antibodySMAD6 Reactivity: Human, Mouse, Rat, Cow, Pig, Dog WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 1-496) antibodySMAD6 Reactivity: Human WB, FACS Host: Mouse Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-385) antibodySMAD6 Reactivity: Human WB, ELISA, IHC, IHC (p) Host: Mouse Monoclonal 1G2 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (N-Term) antibodySMAD6 Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 357-386), (C-Term) antibodySMAD6 Reactivity: Mouse WB Host: Rabbit Polyclonal RB41931 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) antibodySMAD6 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 5H3 unconjugated
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- Application Notes
- The stated application concentrations are suggested starting amounts. Titration of the SMAD6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at 4°C for up to one month. For long term, aliquot the SMAD6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
- Alternative Name
- SMAD6 (SMAD6 Products)
- Synonyms
- madh6 antibody, madh7 antibody, Xsmad6 antibody, hst17432 antibody, AOVD2 antibody, HsT17432 antibody, MADH6 antibody, MADH7 antibody, Madh6 antibody, b2b390Clo antibody, Smad6-like antibody, smad6 antibody, wu:fb22g05 antibody, SMAD family member 6 antibody, SMAD family member 6a antibody, smad6 antibody, SMAD6 antibody, Smad6 antibody, smad6a antibody
- Background
- SMAD6 acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions. [UniProt]
- UniProt
- O43541
- Pathways
- Chromatin Binding
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