CES1 antibody (AA 287-566)

Catalog No. ABIN3015628

This Rabbit Polyclonal antibody specifically detects CES1 in WB. It exhibits reactivity toward Human.

Quick Overview for CES1 antibody (AA 287-566) (ABIN3015628)

Target: CES1 (Carboxylesterase 1 (CES1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CES1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CES1 Antibody

Binding Specificity: AA 287-566

Sequence: RQKTEEELLE TTLKMKFLSL DLQGDPRESQ PLLGTVIDGM LLLKTPEELQ AERNFHTVPY MVGINKQEFG WLIPMLMSYP LSEGQLDQKT AMSLLWKSYP LVCIAKELIP EATEKYLGGT DDTVKKKDLF LDLIADVMFG VPSVIVARNH RDAGAPTYMY EFQYRPSFSS DMKPKTVIGD HGDELFSVFG APFLKEGASE EEIRLSKMVM KFWANFARNG NPNGEGLPHW PEYNQKEGYL QIGANTQAAQ KLKDKEVAFW TNLFAKKAVE KPPQTEHIEL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 287-566 of human CES1 (NP_001257.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CES1

Target: CES1 (Carboxylesterase 1 (CES1))

Alternative Name: CES1

Background: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.,CES1,ACAT,CE-1,CEH,CES2,HMSE,HMSE1,PCE-1,REH,SES1,TGH,hCE-1,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Hydrolysis,Drug metabolism,Immunology & Inflammation,CD markers,Cardiovascular,Lipids,CES1

Molecular Weight: 62 kDa

Gene ID: 1066

UniProt: P23141

Pathways: Monocarboxylic Acid Catabolic Process